DNA Binding Motif

Accessions: 6c2s_AD (3D-footprint 20231221)
Names: Transcriptional regulator, MarR family
Organisms: Rhodopseudomonas palustris, strain ATCC BAA-98 / CGA009
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Transcriptional repressor, CouR, bound to a 23-mer DNA duplex
Length: 21
Consensus: ATnnTTATAnnnTATAAnnAT
Weblogo:
PSSM: P0 A C G T
01 88 2 2 4 A
02 2 2 1 91 T
03 24 24 24 24 n
04 24 24 24 24 n
05 7 6 9 74 T
06 2 4 2 88 T
07 88 2 4 2 A
08 0 0 0 96 T
09 88 4 2 2 A
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 2 2 2 90 T
14 96 0 0 0 A
15 2 9 2 83 T
16 88 2 4 2 A
17 88 4 2 2 A
18 24 24 24 24 n
19 24 24 24 24 n
20 93 0 3 0 A
21 2 4 2 88 T
Binding TFs: 6c2s_A / 6c2s_D (MarR family, MarR family, Winged helix DNA-binding domain)
Binding Sites: 6c2s_U
6c2s_V
Publications: Cogan DP, Baraquet C, Harwood CS, Nair SK. Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, in Rhodopseudomonas palustris. J Biol Chem 293:11727-11735 (2018). [Pubmed]

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