DNA Binding Motif

Accessions: HSF1_full (HumanTF 1.0), MA0486.2 (JASPAR 2024)
Names: HSF1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: trimeric; SELEX cycle: 3, HT-SELEX
Length: 13
Consensus: TTCTaGAAyrTTC
Weblogo:
PSSM: P0 A C G T
01 64 18 25 1455 T
02 11 4 17 1455 T
03 9 1455 9 5 C
04 4 361 238 1455 T
05 1455 424 384 3 a
06 0 0 1455 0 G
07 1455 8 2 7 A
08 1455 4 4 27 A
09 70 713 159 515 y
10 490 190 592 183 r
11 25 5 0 1455 T
12 6 2 4 1455 T
13 3 1455 3 4 C
Type: Heterodimer
Binding TFs: Q00613 (HSF-type DNA-binding, Vertebrate heat shock transcription factor)
HSF1_full (HSF-type DNA-binding)
Q00613
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Reddy T.E, DeLisi C, Shakhnovich B.E. Binding site graphs: a new graph theoretical framework for prediction of transcription factor binding sites. PLoS computational biology 3:e90 (2007). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.