DNA Binding Motif

						

			
Accessions: KLF16_DBD (HumanTF 1.0), MA0741.1 (JASPAR 2024)

			
Names: KLF16
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 11
Consensus: gmCMCgCCCMC
Weblogo: 
PSSM: P0      A      C      G      T
01    666    535   1612    240      g
02    901   1612     77    116      m
03     62   1612      6     45      C
04   1150    461     32      0      M
05     66   1612     17     19      C
06    497    173   1612    403      g
07      8   1612      0      0      C
08      2   1612      8      0      C
09     16   1612      3     97      C
10    437   1175     19     40      M
11     32   1612     23    370      C
Type: Heterodimer
Binding TFs: KLF16_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q9BXK1 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q9BXK1
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Lomberk G, Urrutia R. The family feud: turning off Sp1 by Sp1-like KLF proteins. Biochem J : (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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