DNA Binding Motif

Accessions: 4iqr_AB (3D-footprint 20231221)
Names: Hepatocyte nuclear factor 4-alpha
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Multi-Domain Organization of the HNF4alpha Nuclear Receptor Complex on DNA
Length: 11
Consensus: GACCtnTKaCC
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 72 6 6 12 A
03 4 89 3 0 C
04 0 96 0 0 C
05 12 13 17 54 t
06 24 24 24 24 n
07 3 3 3 87 T
08 0 3 25 68 K
09 65 11 10 10 a
10 0 96 0 0 C
11 0 96 0 0 C
Type: Heterodimer
Binding TFs: 4iqr_A (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
4iqr_B (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
Binding Sites: 4iqr_C
4iqr_D
Publications: Chandra V, Huang P, Potluri N, Wu D, Kim Y, Rastinejad F. Multidomain integration in the structure of the HNF-4α nuclear receptor complex. Nature 495:394-8 (2013). [Pubmed]

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