DNA Binding Motif

Accessions: 5tw1_F (3D-footprint 20231221)
Names: RNA polymerase sigma factor SigA
Organisms: Mycobacterium smegmatis, Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of a Mycobacterium smegmatis transcription initiation complex with RbpA
Length: 25
Consensus: CTTGACAnnnnnnnnnnnnTnTGCT
Weblogo:
PSSM: P0 A C G T
01 7 75 7 7 C
02 0 0 0 96 T
03 7 9 7 73 T
04 0 0 96 0 G
05 96 0 0 0 A
06 0 96 0 0 C
07 73 9 7 7 A
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 24 24 24 24 n
14 24 24 24 24 n
15 24 24 24 24 n
16 24 24 24 24 n
17 24 24 24 24 n
18 24 24 24 24 n
19 24 24 24 24 n
20 7 7 9 73 T
21 24 24 24 24 n
22 0 0 0 96 T
23 0 0 96 0 G
24 0 96 0 0 C
25 0 0 0 96 T
Binding TFs: 5tw1_F (Sigma-70 factor, region 1.2, Sigma-70 region 3, Sigma-70 region 2 , Sigma-70, region 4)
Binding Sites: 5tw1_O
5tw1_P
Publications: Hubin EA, Fay A, Xu C, Bean JM, Saecker RM, Glickman MS, Darst SA, Campbell EA. Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA. Elife : (2017). [Pubmed]

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