DNA Binding Motif

Accessions: 4aa6_E (3D-footprint 20231221)
Names: ESTROGEN RECEPTOR
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation
Length: 6
Consensus: aaGTCA
Weblogo:
PSSM: P0 A C G T
01 60 12 12 12 a
02 60 12 12 12 a
03 0 0 96 0 G
04 0 0 0 96 T
05 0 84 0 12 C
06 96 0 0 0 A
Binding TFs: 4aa6_E (Zinc finger, C4 type (two domains))
Binding Sites: 4aa6_G
4aa6_H
Publications: Schwabe J.W, Chapman L, Rhodes D. The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation. Structure (London, England : 1993) 3:201-13 (1995). [Pubmed]

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