DNA Binding Motif

						

			
Accessions: 6bz1_CD (3D-footprint 20231221)

			
Names: MEF2 CHIMERA
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: MEF2 Chimera D83V mutant/DNA complex
Length: 10
Consensus: cTAnnnntAA
Weblogo: 
PSSM: P0      A      C      G      T
01     16     54     13     13      c
02      0      0      0     96      T
03     96      0      0      0      A
04     24     24     24     24      n
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08     16     13     13     54      t
09     96      0      0      0      A
10     96      0      0      0      A
Type: Heterodimer
Binding TFs: 6bz1_C (SRF-type transcription factor (DNA-binding and dimerisation domain))
6bz1_D (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 6bz1_G
6bz1_H
			
Publications: Lei X, Kou Y, Fu Y, Rajashekar N, Shi H, Wu F, Xu J, Luo Y, Chen L. The Cancer Mutation D83V Induces an α-Helix to β-Strand Conformation Switch in MEF2B. J Mol Biol 430:1157-1172 (2018). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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