DNA Binding Motif

						

			
Accessions: FOXD2_DBD_2 (HumanTF 1.0), MA0847.1 (JASPAR 2024)

			
Names: FOXD2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 2, HT-SELEX
Length: 7
Consensus: rTAAAYA
Weblogo: 
PSSM: P0      A      C      G      T
01    605     53   1261     30      r
02    261    384      0   1866      T
03   1866    281      0    120      A
04   1866     59     20     32      A
05   1866      0      0     35      A
06      0   1361     28    505      Y
07   1866      0    223    176      A
Type: Heterodimer
Binding TFs: FOXD2_DBD (Fork head domain)
O60548 (Fork head domain)
O60548
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Kaufmann E., Mueller D., Knoechel W. DNA recognition site analysis of Xenopus winged helix proteins. J. Mol. Biol. 248:239-254 (1995). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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