DNA Binding Motif

Accessions: 2erg_AB (3D-footprint 20231221)
Names: Regulatory protein LEU3
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of Leu3 DNA-binding domain with a single H50C mutation complexed with a 15mer DNA duplex
Length: 10
Consensus: CCGgnncCGG
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 96 0 0 C
03 0 0 96 0 G
04 13 16 54 13 g
05 24 24 24 24 n
06 24 24 24 24 n
07 13 57 13 13 c
08 0 96 0 0 C
09 0 0 96 0 G
10 0 0 96 0 G
Binding TFs: 2erg_A / 2erg_B (Fungal Zn(2)-Cys(6) binuclear cluster domain)
Binding Sites: 2erg_C / 2erg_D
Publications: Fitzgerald M.X, Rojas J.R, Kim J.M, Kohlhaw G.B, Marmorstein R. Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein. Structure (London, England : 1993) 14:725-35 (2006). [Pubmed]

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