DNA Binding Motif

Accessions: 1osl_AB (3D-footprint 20231221)
Names: Lactose operon repressor
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence
Length: 14
Consensus: ATnAGATATCTTAT
Weblogo:
PSSM: P0 A C G T
01 84 6 3 3 A
02 6 3 3 84 T
03 24 24 24 24 n
04 96 0 0 0 A
05 0 3 92 1 G
06 84 6 3 3 A
07 3 3 3 87 T
08 84 3 6 3 A
09 3 3 3 87 T
10 3 84 3 6 C
11 0 3 1 92 T
12 1 0 3 92 T
13 96 0 0 0 A
14 0 0 0 96 T
Binding TFs: 1osl_A / 1osl_B (Bacterial regulatory proteins, lacI family)
Binding Sites: 1osl_C / 1osl_D
Publications: Kalodimos C.G, Biris N, Bonvin A.M, Levandoski M.M, Guennuegues M, Boelens R, Kaptein R. Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes. Science (New York, N.Y.) 305:386-9 (2004). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.