DNA Binding Motif

Accessions: MA0513.1 (JASPAR 2018)
Names: SMAD2::SMAD3::SMAD4
Organisms: Homo sapiens
Libraries: JASPAR 2018 1
1 Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Cheneby , Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A (2017) JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic Acids Res. doi: 10.1093/nar/gkx1126 [Pubmed]
Notes: ChIP-seq
Length: 13
Consensus: ctGTCTskCACct
Weblogo:
PSSM: P0 A C G T
01 166 432 168 133 c
02 196 75 34 594 t
03 14 8 877 0 G
04 33 45 103 718 T
05 0 899 0 0 C
06 0 0 0 899 T
07 106 231 539 23 s
08 211 125 280 283 k
09 0 896 3 0 C
10 765 19 18 97 A
11 30 736 133 0 C
12 117 583 47 152 c
13 110 214 35 540 t
Binding TFs: Q13485 (MH1 domain, MH2 domain)
Binding Sites: MA0513.1.1
MA0513.1.10
MA0513.1.11
MA0513.1.12
MA0513.1.13
MA0513.1.14
MA0513.1.15
MA0513.1.16
MA0513.1.17
MA0513.1.18
MA0513.1.19
MA0513.1.2
MA0513.1.20
MA0513.1.3
MA0513.1.4
MA0513.1.5
MA0513.1.6
MA0513.1.7
MA0513.1.8
MA0513.1.9
Publications: Shi Y., Wang Y. F., Jayaraman L., Yang H., Massague J., Pavletich N. P. Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling. Cell 94:585-594 (1998). [Pubmed]

Disclaimer

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research.