DNA Binding Motif
| Accessions: | HMBOX1_DBD (HumanTF 1.0), MA0895.1 (JASPAR 2024) |
| Names: | HMBOX1 |
| Organisms: | Mus musculus, Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: monomeric; SELEX cycle: 4, HT-SELEX |
| Length: | 10 |
| Consensus: | myTAGTTAms |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 487 449 194 101 m 02 122 683 186 547 y 03 75 25 63 1231 T 04 1231 0 367 44 A 05 2 51 1231 5 G 06 26 1 5 1231 T 07 237 50 8 1231 T 08 1231 4 17 102 A 09 753 478 130 140 m 10 202 542 370 117 s |
| Type: | Heterodimer |
| Binding TFs: | Q6NT76 (Homeobox domain, Hepatocyte nuclear factor 1 (HNF-1), N terminus) HMBOX1_DBD (Homeobox domain, Homeobox KN domain) Q6NT76 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
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