DNA Binding Motif
| Accessions: | NR2F1_DBD_3 (HumanTF 1.0), MA0017.2 (JASPAR 2024) |
| Names: | NR2F1 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: monomeric; SELEX cycle: 4; Seed was extended with DNNN and NNNH to exclude signal from dimeric site, HT-SELEX |
| Length: | 13 |
| Consensus: | carRGGTCAmrrG |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 4802 11446 3276 3980 c 02 7266 1692 1153 1948 a 03 6333 387 4869 469 r 04 8496 0 3791 0 R 05 0 30 12059 0 G 06 0 0 12059 0 G 07 0 0 0 12059 T 08 0 12059 0 0 C 09 12059 0 91 0 A 10 5116 3055 1618 2270 m 11 3229 2966 4395 1469 r 12 3276 2470 3886 2427 r 13 5681 2912 36863 3466 G |
| Type: | Heterodimer |
| Binding TFs: | P10589 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains)) NR2F1_DBD (Zinc finger, C4 type (two domains)) P10589 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Kimura A., Nishiyori A., Murakami T., Tsukamoto T., Hata S., Osumi T., Okamura R., Mori M., Takiguchi M. Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) represses transcription from the promoter of the gene for ornithine transcarbamylase in a manner antagonistic to hepatocyte nuclear factor-4 (HNF-4). J. Biol. Chem. 268:11125-11133 (1993). [Pubmed] |
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