DNA Binding Motif
| Accessions: | BACH1 (HumanTF2 1.0), MA1633.2 (JASPAR 2024) |
| Names: | BACH1 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF2 1.0 1, JASPAR 2024 2 1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: heterodimeric; Experiment type: HT-SELEX; HT-SELEX generated reference PWM, HT-SELEX |
| Length: | 9 |
| Consensus: | ATGACTCAt |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 32322 1482 6187 1048 A 02 7 25 25 32322 T 03 0 13 32322 811 G 04 32322 38 24 14 A 05 551 32322 0 517 C 06 534 31 3303 32322 T 07 2834 32322 52 18 C 08 32322 39 50 17 A 09 4970 8737 2962 32322 t |
| Type: | Heterodimer |
| Binding TFs: | O14867 (bZIP transcription factor, BTB/POZ domain, Basic region leucine zipper) BACH1_TF2 (bZIP transcription factor, bZIP Maf transcription factor, Basic region leucine zipper) O14867 |
| Publications: | Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed] Oyake T., Itoh K., Motohashi H., Hayashi N., Hoshino H., Nishizawa M., Yamamoto M., Igarashi K. Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol. Cell. Biol. 16:6083-6095 (1996). [Pubmed] |
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