DNA Binding Motif

Accessions: 6t78_AB (3D-footprint 20231221)
Names: Transcription factor SOX-11
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of human Sox11 transcription factor in complex with a short DNA fragment
Length: 12
Consensus: ACAATAAATTGT
Weblogo:
PSSM: P0 A C G T
01 89 0 7 0 A
02 6 76 6 8 C
03 96 0 0 0 A
04 70 12 6 8 A
05 0 0 0 96 T
06 96 0 0 0 A
07 96 0 0 0 A
08 89 1 6 0 A
09 6 7 0 83 T
10 0 0 0 96 T
11 6 14 70 6 G
12 0 0 0 96 T
Type: Heterodimer
Binding TFs: 6t78_A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
6t78_B (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 6t78_C
6t78_D
Publications: Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P. Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature 580:669-672 (2020). [Pubmed]

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