DNA Binding Motif

Accessions: 4yg4_ABCD (3D-footprint 20210203)
Names: Antitoxin HipB
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: HipB-O1-O1* complex
Length: 15
Consensus: ATaCnnnnnnngGGA
Weblogo:
PSSM: P0 A C G T
01 96 0 0 0 A
02 0 0 0 96 T
03 64 14 12 6 a
04 6 66 12 12 C
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 15 12 57 12 g
13 0 0 96 0 G
14 0 0 96 0 G
15 83 13 0 0 A
Type: Heterodimer
Binding TFs: 4yg4_B (Helix-turn-helix domain, Helix-turn-helix domain, Helix-turn-helix domain, Helix-turn-helix, Cro/C1-type HTH DNA-binding domain)
4yg4_D / 4yg4_C / 4yg4_A (Helix-turn-helix domain, Helix-turn-helix domain, Helix-turn-helix domain, Helix-turn-helix, Cro/C1-type HTH DNA-binding domain)
Binding Sites: 4yg4_F
4yg4_T
Publications: Schumacher MA, Balani P, Min J, Chinnam NB, Hansen S, Vulić M, Lewis K, Brennan RG. HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature 524:59-64 (2015). [Pubmed]

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