DNA Binding Motif

						

			
Accessions: 2hzv_ABCD (3D-footprint 2022-04-03)

			
Names: Nickel-responsive regulator
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: NikR-operator DNA complex
Length: 28
Consensus: GTyTGAnnnnnnnnnnnnnnnnTCAwAC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0      0     96      T
03      8     24      8     56      y
04      0      0      0     96      T
05      0      0     96      0      G
06     96      0      0      0      A
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13     24     24     24     24      n
14     24     24     24     24      n
15     24     24     24     24      n
16     24     24     24     24      n
17     24     24     24     24      n
18     24     24     24     24      n
19     24     24     24     24      n
20     24     24     24     24      n
21     24     24     24     24      n
22     24     24     24     24      n
23      0      0      0     96      T
24      0     96      0      0      C
25     80      0     16      0      A
26     48      8     16     24      w
27     96      0      0      0      A
28      0     96      0      0      C
Binding TFs: 2hzv_A / 2hzv_B / 2hzv_C / 2hzv_D (Ribbon-helix-helix protein, copG family, NikR C terminal nickel binding domain)
Binding Sites: 2hzv_I
2hzv_J
			
Publications: Schreiter E.R, Wang S.C, Zamble D.B, Drennan C.L. NikR-operator complex structure and the mechanism of repressor activation by metal ions. Proceedings of the National Academy of Sciences of the United States of America 103:13676-81 (2006). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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