DNA Binding Motif

Accessions: 2i13_A (3D-footprint 20231221)
Names: Aart
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Aart, a six finger zinc finger designed to recognize ANN triplets
Length: 18
Consensus: CCCGGGCTTTTCCCTACA
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 96 0 0 C
03 0 96 0 0 C
04 0 0 96 0 G
05 9 0 76 11 G
06 11 9 67 9 G
07 0 96 0 0 C
08 0 0 0 96 T
09 0 0 0 96 T
10 0 0 0 96 T
11 0 0 0 96 T
12 0 96 0 0 C
13 0 96 0 0 C
14 0 96 0 0 C
15 0 0 0 96 T
16 86 10 0 0 A
17 0 96 0 0 C
18 69 9 9 9 A
Binding TFs: 2i13_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: 2i13_C
2i13_D
Publications: Segal D.J, Crotty J.W, Bhakta M.S, Barbas C.F, Horton N.C. Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA. Journal of molecular biology 363:405-21 (2006). [Pubmed]

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