DNA Binding Motif

						

			
Accessions: 4s0h_AB (3D-footprint 20231221)

			
Names: T-box transcription factor TBX5
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: TBX5 DB, NKX2.5 HD, ANF DNA Complex
Length: 13
Consensus: CacnnnnGAAGnG
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02     64      6     13     13      a
03     13     61     16      6      c
04     24     24     24     24      n
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08      6      6     71     13      G
09     82      6      8      0      A
10     96      0      0      0      A
11      0      0     96      0      G
12     24     24     24     24      n
13      0      0     96      0      G
Type: Heterodimer
Binding TFs: 4s0h_A (T-box)
4s0h_B (Homeobox domain)
Binding Sites: 4s0h_C
4s0h_D
			
Publications: Pradhan L, Gopal S, Li S, Ashur S, Suryanarayanan S, Kasahara H, Nam HJ. Intermolecular Interactions of Cardiac Transcription Factors NKX2. 5 and TBX5 55:1702-10 (Biochemistry.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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