DNA Binding Motif

Accessions: 6erp_BGJ (3D-footprint 20231221)
Names: Transcription factor A, mitochondrial
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the human mitochondrial transcription initiation complex at the LSP promoter
Length: 34
Consensus: AGTTGGnnnnnnnCTGTTnnnnnnnnnnnnCnTG
Weblogo:
PSSM: P0 A C G T
01 67 9 9 11 A
02 0 0 96 0 G
03 0 0 0 96 T
04 0 0 0 96 T
05 0 0 96 0 G
06 0 0 96 0 G
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 24 24 24 24 n
14 0 96 0 0 C
15 0 0 0 96 T
16 0 0 96 0 G
17 0 0 0 96 T
18 9 9 11 67 T
19 24 24 24 24 n
20 24 24 24 24 n
21 24 24 24 24 n
22 24 24 24 24 n
23 24 24 24 24 n
24 24 24 24 24 n
25 24 24 24 24 n
26 24 24 24 24 n
27 24 24 24 24 n
28 24 24 24 24 n
29 24 24 24 24 n
30 24 24 24 24 n
31 0 96 0 0 C
32 24 24 24 24 n
33 0 0 0 96 T
34 9 9 69 9 G
Binding TFs: 6erp_G (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 6erp_H
6erp_I
Publications: Hillen HS, Morozov YI, Sarfallah A, Temiakov D, Cramer P. Structural Basis of Mitochondrial Transcription Initiation. Cell 171:1072-1081 (2017). [Pubmed]

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