DNA Binding Motif

Accessions: 1mjo_ABCD (3D-footprint 20231221)
Names: METHIONINE REPRESSOR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: METHIONINE HOLOREPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR WITH THE CENTRAL TA STEP MUTATED TO AT
Length: 16
Consensus: rGACGTCaTGACGACT
Weblogo:
PSSM: P0 A C G T
01 34 0 59 3 r
02 0 0 96 0 G
03 96 0 0 0 A
04 0 92 3 1 C
05 19 1 75 1 G
06 0 0 0 96 T
07 0 96 0 0 C
08 63 17 7 9 a
09 4 3 3 86 T
10 0 0 96 0 G
11 96 0 0 0 A
12 0 89 0 7 C
13 5 1 90 0 G
14 71 3 3 19 A
15 0 96 0 0 C
16 4 5 1 86 T
Binding TFs: 1mjo_A / 1mjo_B / 1mjo_C / 1mjo_D (Met Apo-repressor, MetJ)
Binding Sites: 1mjo_F / 1mjo_G
Publications: Garvie C.W, Phillips S.E. Direct and indirect readout in mutant Met repressor-operator complexes. Structure (London, England : 1993) 8:905-14 (2000). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.