DNA Binding Motif

Accessions: 6byy_AB (3D-footprint 20231221)
Names: MEF2 CHIMERA
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: MEF2 CHIMERA/DNA Complex
Length: 9
Consensus: TAnnnnTAG
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 67 9 9 11 A
03 24 24 24 24 n
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 9 11 9 67 T
08 86 0 10 0 A
09 9 2 76 9 G
Binding TFs: 6byy_A / 6byy_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 6byy_K
6byy_L
Publications: Lei X, Kou Y, Fu Y, Rajashekar N, Shi H, Wu F, Xu J, Luo Y, Chen L. The Cancer Mutation D83V Induces an α-Helix to β-Strand Conformation Switch in MEF2B. J Mol Biol 430:1157-1172 (2018). [Pubmed]

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