DNA Binding Motif

Accessions: 6w1a_AB (3D-footprint 20231221)
Names: Transcriptional regulator
Organisms: Streptococcus dysgalactiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2 bound to DNA
Length: 12
Consensus: CcCasywdcACa
Weblogo:
PSSM: P0 A C G T
01 4 82 5 5 C
02 8 64 11 13 c
03 3 85 5 3 C
04 61 12 12 11 a
05 23 27 24 22 s
06 22 24 23 27 y
07 25 23 23 25 w
08 25 23 24 24 d
09 17 40 17 22 c
10 94 0 2 0 A
11 8 69 6 13 C
12 60 12 12 12 a
Type: Heterodimer
Binding TFs: 6w1a_A (Helix-turn-helix, Helix-turn-helix domain)
6w1a_B (Helix-turn-helix, Helix-turn-helix domain)
Binding Sites: 6w1a_E
6w1a_F
Publications: Capodagli GC, Tylor KM, Kaelber JT, Petrou VI, Federle MJ, Neiditch MB. Structure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay. Proc Natl Acad Sci U S A 117:24494-24502 (2020). [Pubmed]

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