DNA Binding Motif

Accessions: 5d5v_BD (3D-footprint 20231221)
Names: Heat shock factor protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of human Hsf1 with Satellite III repeat DNA
Length: 8
Consensus: GGAnTGGA
Weblogo:
PSSM: P0 A C G T
01 6 6 78 6 G
02 0 0 96 0 G
03 78 6 6 6 A
04 24 24 24 24 n
05 6 6 9 75 T
06 0 0 90 6 G
07 0 0 96 0 G
08 78 6 6 6 A
Type: Heterodimer
Binding TFs: 5d5v_B (HSF-type DNA-binding)
5d5v_D (HSF-type DNA-binding)
Binding Sites: 5d5v_A
5d5v_C
Publications: Neudegger T, Verghese J, Hayer-Hartl M, Hartl FU, Bracher A. Structure of human heat-shock transcription factor 1 in complex with DNA. Nat Struct Mol Biol 23:140-6 (2016). [Pubmed]

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