DNA Binding Motif

Accessions: 5vxn_AB (3D-footprint 20231221)
Names: Transcriptional regulatory protein RcsB
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of two RcsB dimers bound to two parallel DNAs.
Length: 14
Consensus: TAAGAnnnnTCCTA
Weblogo:
PSSM: P0 A C G T
01 6 6 6 78 T
02 96 0 0 0 A
03 78 6 6 6 A
04 6 6 78 6 G
05 96 0 0 0 A
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 0 0 0 96 T
11 0 96 0 0 C
12 0 96 0 0 C
13 6 6 6 78 T
14 78 6 6 6 A
Type: Heterodimer
Binding TFs: 5vxn_A (Response regulator receiver domain, Bacterial regulatory proteins, luxR family, Sigma-70, region 4)
5vxn_B (Response regulator receiver domain, Bacterial regulatory proteins, luxR family)
Binding Sites: 5vxn_E
5vxn_F
Publications: Filippova EV, Zemaitaitis B, Aung T, Wolfe AJ, Anderson WF. Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB. MBio : (2018). [Pubmed]

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