DNA Binding Motif

Accessions: 1gt0_D (3D-footprint 20231221)
Names: TRANSCRIPTION FACTOR SOX-2
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of a POU/HMG/DNA ternary complex
Length: 9
Consensus: CTTTGTnng
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 0 0 96 T
03 0 0 0 96 T
04 0 0 0 96 T
05 20 0 76 0 G
06 0 0 0 96 T
07 24 24 24 24 n
08 24 24 24 24 n
09 19 20 38 19 g
Binding TFs: 1gt0_D (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 1gt0_A
1gt0_B
Publications: Reményi A, Lins K, Nissen L.J, Reinbold R, Schöler H.R, Wilmanns M. Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes & development 17:2048-59 (2003). [Pubmed]

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