DNA Binding Motif

Accessions: 6p0t_ABE (3D-footprint 20231221)
Names: DNA-binding protein Fis
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ternary DNA complex "FX(1-2)-1Xis" containing E. coli Fis and phage lambda Xis
Length: 20
Consensus: TGTnTTnnnnACAGACTAnA
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 3 3 87 3 G
03 0 0 0 96 T
04 24 24 24 24 n
05 3 3 3 87 T
06 0 0 0 96 T
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 84 3 6 3 A
12 0 96 0 0 C
13 84 3 3 6 A
14 6 3 84 3 G
15 96 0 0 0 A
16 0 96 0 0 C
17 3 6 3 84 T
18 81 3 7 5 A
19 24 24 24 24 n
20 84 3 3 6 A
Type: Heterodimer
Binding TFs: 6p0t_B (Bacterial regulatory protein, Fis family)
6p0t_A (Bacterial regulatory protein, Fis family)
Binding Sites: 6p0t_C
6p0t_D
Publications: Hancock SP, Cascio D, Johnson RC. Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res 47:8874-8887 (2019). [Pubmed]

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