DNA Binding Motif

						

			
Accessions: 6ide_AB (3D-footprint 20231221)

			
Names: Transcriptional regulator LuxR family
Organisms: Vibrio cholerae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the Vibrio cholera VqmA-Ligand-DNA complex provides molecular mechanisms for drug design
Length: 12
Consensus: GGGgnnnncCcC
Weblogo: 
PSSM: P0      A      C      G      T
01      9      9     67     11      G
02      9      9     69      9      G
03      7      8     74      7      G
04     20     22     34     20      g
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09     20     36     20     20      c
10      9     67      9     11      C
11     13     63     10     10      c
12      8     72      8      8      C
Type: Heterodimer
Binding TFs: 6ide_A (Bacterial regulatory proteins, luxR family, PAS fold)
6ide_B (Bacterial regulatory proteins, luxR family, PAS fold)
Binding Sites: 6ide_C
6ide_D
			
Publications: Wu H, Li M, Guo H, Zhou H, Li B, Xu Q, Xu C, Yu F, He J. Crystal structure of the Vibrio cholerae VqmA-ligand-DNA complex provides insight into ligand-binding mechanisms relevant for drug design. J Biol Chem 294:2580-2592 (2019). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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