DNA Binding Motif

						

			
Accessions: MA1119.1 (JASPAR 2024)

			
Names: SIX2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 16
Consensus: wwcTGaAACCTGAtmy
Weblogo: 
PSSM: P0      A      C      G      T
01   1673   1234   1145   1401      w
02   1607   1242   1226   1378      w
03    963   2910    828    752      c
04    840    215    561   3837      T
05    165     56   5065    167      G
06   3578    319    273   1283      a
07   4885    264     66    238      A
08   5275     39     74     65      A
09    190   4367    170    726      C
10    586   4169    196    502      C
11    325    295    175   4658      T
12    321    114   4830    188      G
13   5202     75     85     91      A
14    553    615   1193   3092      t
15   2415   1812    563    663      m
16    858   2523    511   1561      y
Type: Heterodimer
Binding TFs: Q9NPC8 (Homeobox domain, Homeobox KN domain)
Q9NPC8
Binding Sites: MA1119.1.1
MA1119.1.10
MA1119.1.11
MA1119.1.12
MA1119.1.13
MA1119.1.14
MA1119.1.15
MA1119.1.16
MA1119.1.17
MA1119.1.18
MA1119.1.19
MA1119.1.2
MA1119.1.20
MA1119.1.3
MA1119.1.4
MA1119.1.5
MA1119.1.6
MA1119.1.7
MA1119.1.8
MA1119.1.9
			
Publications: Brodbeck S, Besenbeck B, Englert C. The transcription factor Six2 activates expression of the Gdnf gene as well as its own promoter. Mech Dev 121:1211-22 (2004). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.