DNA Binding Motif
| Accessions: | BHLHE41_full (HumanTF 1.0), MA0636.1 (JASPAR 2024) |
| Names: | BHLHE41 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: dimeric; SELEX cycle: 3, HT-SELEX |
| Length: | 10 |
| Consensus: | rTCACGTGAc |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 2894 1046 5574 59 r 02 98 17 1831 5574 T 03 2 5574 3 1 C 04 5574 12 21 3 A 05 1 5574 1 5 C 06 2 1 5574 0 G 07 19 16 16 5574 T 08 1 1 5574 0 G 09 5574 1229 7 23 A 10 74 5574 985 1963 c |
| Type: | Heterodimer |
| Binding TFs: | BHLHE41_full / Q9C0J9 (Helix-loop-helix DNA-binding domain, Hairy Orange) Q9C0J9 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Nakamura H., Tanimoto K., Hiyama K., Yunokawa M., Kawamoto T., Kato Y., Yoshiga K., Poellinger L., Hiyama E., Nishiyama M. Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2.. Oncogene 27:4200-4209 (2008). [Pubmed] |
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