DNA Binding Motif

						

			
Accessions: TBX21_full_2 (HumanTF 1.0), MA0690.1 (JASPAR 2024)

			
Names: TBX21
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 3, HT-SELEX
Length: 10
Consensus: aAGGTGTGAA
Weblogo: 
PSSM: P0      A      C      G      T
01   2322    263    937    872      a
02   4395     30    359    146      A
03    612    239   4395    398      G
04      2     17   4395     33      G
05      6    180     16   4395      T
06      1      0   4395      2      G
07    185    331     34   4395      T
08     80    126   4395    364      G
09   4395      0     38      0      A
10   4395    441    317   1287      A
Type: Heterodimer
Binding TFs: TBX21_full (T-box)
Q9UL17 (T-box)
Q9UL17
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Naiche LA, Harrelson Z, Kelly RG, Papaioannou VE. T-box genes in vertebrate development. Annu Rev Genet : (2005;39:219-39.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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