DNA Binding Motif

Accessions: 3d6y_A (3D-footprint 2022-04-03)
Names: Multidrug-efflux transporter 1 regulator
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of R275E mutant of BMRR bound to DNA and berberine
Length: 4
Consensus: CCCT
Weblogo:
PSSM: P0 A C G T
01 9 67 9 11 C
02 11 67 9 9 C
03 9 69 9 9 C
04 0 0 0 96 T
Binding TFs: 3d6y_A (MerR family regulatory protein, GyrI-like small molecule binding domain, MerR HTH family regulatory protein)
Binding Sites: 3d6y_B
Publications: Newberry K.J, Huffman J.L, Miller M.C, Vazquez-Laslop N, Neyfakh A.A, Brennan R.G. Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion. The Journal of biological chemistry 283:26795-804 (2008). [Pubmed]

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