DNA Binding Motif

						

			
Accessions: Hnf4a_DBD (HumanTF 1.0), MA0114.3 (JASPAR 2024)

			
Names: Hnf4a
Organisms: Mus musculus
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 16
Consensus: rRGGTCAAAGTCCAat
Weblogo: 
PSSM: P0      A      C      G      T
01   1870    587   3292    467      r
02   1624     23   3538      5      R
03      6      0   5162      1      G
04    211     14   5162    711      G
05    148     66    564   5162      T
06      1   5162      5    122      C
07   5162      2    159      0      A
08   5162      0     69     11      A
09   5162      0     52      0      A
10      0      1   5162      3      G
11      0      5      7   5162      T
12    129   5162    131    962      C
13      0   5162      4    191      C
14   4452     35    709    135      A
15   2148   1109   1121    784      a
16   1019   1064    906   2174      t
Type: Heterodimer
Binding TFs: Hnf4a_DBD (Zinc finger, C4 type (two domains))
P49698 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
P49698
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Ellrott K, Yang C, Sladek F.M, Jiang T. Identifying transcription factor binding sites through Markov chain optimization. Bioinformatics (Oxford, England) 18 Suppl 2:S100-9 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.