DNA Binding Motif

Accessions: 1nkp_AB (3D-footprint 2022-04-03)
Names: Myc proto-oncogene protein
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Myc-Max recognizing DNA
Length: 9
Consensus: gCACGTGCT
Weblogo:
PSSM: P0 A C G T
01 9 9 57 21 g
02 0 96 0 0 C
03 96 0 0 0 A
04 0 96 0 0 C
05 0 0 96 0 G
06 0 0 0 96 T
07 0 0 96 0 G
08 9 69 9 9 C
09 9 9 9 69 T
Type: Heterodimer
Binding TFs: 1nkp_A (Helix-loop-helix DNA-binding domain, Myc leucine zipper domain)
1nkp_B (Helix-loop-helix DNA-binding domain)
Binding Sites: 1nkp_F / 1nkp_G
Publications: Nair S.K, Burley S.K. X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors. Cell 112:193-205 (2003). [Pubmed]

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