DNA Binding Motif

						

			
Accessions: Klf12_DBD (HumanTF 1.0), MA0742.1 (JASPAR 2024)

			
Names: Klf12
Organisms: Mus musculus
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 15
Consensus: GrCCACGCCCwthtw
Weblogo: 
PSSM: P0      A      C      G      T
01    167     35   1158    225      G
02    553     11    531      0      r
03     19    668      8      9      C
04      5    670     12      3      C
05    853     27      2      0      A
06      9    675      0      4      C
07    215      1   1348     16      G
08      0    687      0      4      C
09      0    706      9     13      C
10      0    715      0     13      C
11    410    120      0    483      w
12    238    219     99    403      t
13    308    239     84    290      h
14    238    186    117    429      t
15    271    210    141    330      w
Type: Heterodimer
Binding TFs: Klf12_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
O35738 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
O35738
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Lomberk G, Urrutia R. The family feud: turning off Sp1 by Sp1-like KLF proteins. Biochem J : (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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