DNA Binding Motif
| Accessions: | PRRX1_DBD (HumanTF 1.0), MA0716.1 (JASPAR 2024) |
| Names: | PRRX1 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: monomeric; SELEX cycle: 2, HT-SELEX |
| Length: | 8 |
| Consensus: | yyAATTAr |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 4132 9063 4339 6364 y 02 2373 11122 1121 12775 y 03 23897 1088 1776 810 A 04 23897 503 202 209 A 05 0 3 0 23897 T 06 1264 2302 1004 23897 T 07 23897 644 136 1229 A 08 9498 4269 6366 3765 r |
| Type: | Heterodimer |
| Binding TFs: | PRRX1_DBD (Homeobox domain) P54821 (Homeobox domain, OAR domain) P54821 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
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