DNA Binding Motif

Accessions: CUX1_HOXA13_2 (HumanTF2 1.0)
Names: CUX1_HOXA13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: cyCrTAAAwATyGATc
Weblogo:
PSSM: P0 A C G T
01 474 3974 767 1207 c
02 467 2627 38 3795 y
03 869 5552 220 1103 C
04 3806 111 2615 60 r
05 21 113 27 6422 T
06 6422 237 138 1558 A
07 6422 113 40 244 A
08 6422 175 134 117 A
09 2952 1139 584 1746 w
10 6422 0 6 79 A
11 18 4 1 6422 T
12 157 3344 630 3078 y
13 61 0 6422 13 G
14 6422 293 732 67 A
15 145 494 248 6422 T
16 447 3788 1123 1064 c
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
HOXA13_TF2 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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