DNA Binding Motif

Accessions: GLI2_DBD_2 (HumanTF 1.0), MA0734.1 (JASPAR 2024)
Names: GLI2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 3, HT-SELEX
Length: 12
Consensus: gCGACCACmCwr
Weblogo:
PSSM: P0 A C G T
01 348 184 1437 203 g
02 128 1437 116 83 C
03 16 10 1437 36 G
04 1437 148 29 15 A
05 6 1437 6 8 C
06 0 1437 8 4 C
07 1437 21 6 14 A
08 5 1437 9 5 C
09 709 386 233 109 m
10 314 1437 92 137 C
11 671 117 215 1437 w
12 843 221 1437 308 r
Type: Heterodimer
Binding TFs: GLI2_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
P10070 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
P10070
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Kinzler K. W., Vogelstein B. The GLI Gene Encodes a Nuclear Protein Which Binds Specific Sequences in the Human Genome. Mol. Cell. Biol. 10:634-642 (1990). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.