DNA Binding Motif

Accessions: 4f6n_A (3D-footprint 20231221)
Names: Transcriptional regulator Kaiso
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA
Length: 9
Consensus: gannnnGng
Weblogo:
PSSM: P0 A C G T
01 19 19 39 19 g
02 63 13 10 10 a
03 24 24 24 24 n
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 7 7 74 8 G
08 24 24 24 24 n
09 13 14 56 13 g
Binding TFs: 4f6n_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 4f6n_D
4f6n_E
Publications: Buck-Koehntop B.A, Stanfield R.L, Ekiert D.C, Martinez-Yamout M.A, Dyson H.J, Wilson I.A, Wright P.E. Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proceedings of the National Academy of Sciences of the United States of America 109:15229-34 (2012). [Pubmed]

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