DNA Binding Motif

						

			
Accessions: ZNF740_DBD (HumanTF 1.0), MA0753.1 (JASPAR 2024)

			
Names: ZNF740
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 10
Consensus: mCCCCCCCAc
Weblogo: 
PSSM: P0      A      C      G      T
01    589    995    382    185      m
02    196   2151     27    145      C
03    146   2151      7     49      C
04     21   2151      8     34      C
05     20   2151     12     33      C
06      8   2151     21     30      C
07     53   2151     38     23      C
08    108   2151     23    104      C
09   2151    587    114    310      A
10    433   2151    184    708      c
Type: Heterodimer
Binding TFs: ZNF740_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q8NDX6 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q8NDX6
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Weirauch MT, Cote A, Norel R, Annala M, Zhao Y, Riley TR, Saez-Rodriguez J, Cokelaer T, Vedenko A, Talukder S; DREAM5 Consortium, Bussemaker HJ, Morris QD, Bulyk ML, Stolovitzky G, Hughes TR. Evaluation of methods for modeling transcription factor sequence specificity. Nat Biotechnol 31:126-34 (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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