DNA Binding Motif

						

			
Accessions: TBX2_full_2 (HumanTF 1.0), MA0688.1 (JASPAR 2024)

			
Names: TBX2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 11
Consensus: wAGGTGTgAaa
Weblogo: 
PSSM: P0      A      C      G      T
01   1258    402    717    804      w
02   3181     59    716    442      A
03    602    519   3181    353      G
04      9     36   3181     14      G
05      0    329     21   3181      T
06     26      0   3181     12      G
07    307    392     27   3181      T
08    310   1289   3181   1409      g
09   3181     26    125    120      A
10   2525    491    527    656      a
11   1477    446    590    667      a
Type: Heterodimer
Binding TFs: TBX2_full (T-box, T-box transcription factor)
Q13207 (T-box, T-box transcription factor)
Q13207
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Naiche LA, Harrelson Z, Kelly RG, Papaioannou VE. T-box genes in vertebrate development. Annu Rev Genet : (2005;39:219-39.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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