DNA Binding Motif

Accessions: 1yrn_AB (3D-footprint 20231221)
Names: PROTEIN (MAT A1 HOMEODOMAIN)
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA
Length: 17
Consensus: TGTAawTnnTtnCnTCA
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 0 0 96 0 G
03 2 0 1 93 T
04 96 0 0 0 A
05 56 16 16 8 a
06 52 3 14 27 w
07 2 2 2 90 T
08 24 24 24 24 n
09 24 24 24 24 n
10 0 2 2 92 T
11 10 8 16 62 t
12 24 24 24 24 n
13 2 89 3 2 C
14 24 24 24 24 n
15 0 0 0 96 T
16 0 96 0 0 C
17 90 2 2 2 A
Type: Heterodimer
Binding TFs: 1yrn_B (Homeobox domain, Homeobox KN domain)
1yrn_A (Homeobox domain, Homeobox KN domain)
Binding Sites: 1yrn_C
1yrn_D
Publications: Li T, Stark M.R, Johnson A.D, Wolberger C. Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA. Science (New York, N.Y.) 270:262-9 (1995). [Pubmed]

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