DNA Binding Motif

Accessions: 1k78_EF (3D-footprint 20231221)
Names: Paired Box Protein Pax5
Organisms: Homo sapiens, Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Pax5(1-149)+Ets-1(331-440)+DNA
Length: 19
Consensus: CGGAGAnnnGnnnnanngG
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 0 96 0 G
03 0 0 96 0 G
04 96 0 0 0 A
05 0 0 96 0 G
06 80 5 6 5 A
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 10 15 66 5 G
11 24 24 24 24 n
12 24 24 24 24 n
13 24 24 24 24 n
14 24 24 24 24 n
15 60 10 11 15 a
16 24 24 24 24 n
17 24 24 24 24 n
18 11 10 65 10 g
19 10 1 85 0 G
Type: Heterodimer
Binding TFs: 1k78_E ('Paired box' domain)
1k78_F (Ets-domain)
Binding Sites: 1k78_G
1k78_H
1k78_D
Publications: Garvie C. W., Hagman J., Wolberger C. Structural studies of Ets-1/Pax5 complex formation on DNA.. Mol. Cell 8:1267-1276 (2001). [Pubmed]

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