DNA Binding Motif
| Accessions: | UP00584F_2 (UniPROBE 20160601) |
| Names: | Aristaless-related homeobox, ARX_T333N_R2, CT121, EIEE1, homeobox protein ARX, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS |
| Organisms: | Homo sapiens |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 22 |
| Consensus: | mAkrdyrCyAATTrGckrwtgm |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.35 0.25 0.24 0.16 m 02 0.72 0.10 0.09 0.09 A 03 0.15 0.23 0.28 0.34 k 04 0.32 0.08 0.39 0.21 r 05 0.33 0.13 0.26 0.29 d 06 0.09 0.41 0.18 0.32 y 07 0.28 0.22 0.46 0.04 r 08 0.05 0.73 0.04 0.17 C 09 0.01 0.44 0.01 0.55 y 10 0.98 0 0.01 0.01 A 11 0.99 0 0 0.01 A 12 0.01 0 0 0.99 T 13 0.01 0.01 0 0.98 T 14 0.55 0.01 0.44 0.01 r 15 0.17 0.04 0.73 0.05 G 16 0.07 0.52 0.18 0.24 c 17 0.11 0.16 0.33 0.40 k 18 0.30 0.17 0.37 0.15 r 19 0.29 0.20 0.20 0.31 w 20 0.16 0.13 0.19 0.52 t 21 0.16 0.15 0.47 0.22 g 22 0.40 0.26 0.16 0.18 m |
| Binding TFs: | UP00584F (Homeobox domain) |
| Binding Sites: | GGTAATTA ACCAATTA ACTAATTA ACTAATTG ATAATTAG ATAATTGG ATTAATTA CCAATTAA CCAATTAG CCCAATTA CCTAATTA CTAATTAA CTAATTAC CTAATTAG CTTAATTA GCCAATTA GCTAATTA GTTAATTA TTAATTAA CCAATTAC |
| Publications: | Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed] |
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