DNA Binding Motif

						

			
Accessions: 5zx2_F (3D-footprint 20231221)

			
Names: ECF RNA polymerase sigma factor SigH
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA
Length: 31
Consensus: GGGTnTACcACnnnnnnnnnnnnnnnGTnCC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      6      4     82      4      G
03      0      0     96      0      G
04      9     10      9     68      T
05     24     24     24     24      n
06      0      0      0     96      T
07     96      0      0      0      A
08      0     96      0      0      C
09     13     65      9      9      c
10     82      6      4      4      A
11      9     68     10      9      C
12     24     24     24     24      n
13     24     24     24     24      n
14     24     24     24     24      n
15     24     24     24     24      n
16     24     24     24     24      n
17     24     24     24     24      n
18     24     24     24     24      n
19     24     24     24     24      n
20     24     24     24     24      n
21     24     24     24     24      n
22     24     24     24     24      n
23     24     24     24     24      n
24     24     24     24     24      n
25     24     24     24     24      n
26     24     24     24     24      n
27      0      0     96      0      G
28      0      0      5     91      T
29     24     24     24     24      n
30      0     96      0      0      C
31      0     96      0      0      C
Binding TFs: 5zx2_F (Sigma-70 region 2 , Sigma-70, region 4, Sigma-70, region 4)
Binding Sites: 5zx2_G
5zx2_H
			
Publications: Li L, Fang C, Zhuang N, Wang T, Zhang Y. Structural basis for transcription initiation by bacterial ECF σ factors. Nat Commun 10:1153 (2019). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.