DNA Binding Motif
Accessions: | IRF5_full_1 (HumanTF 1.0), MA1420.1 (JASPAR 2024) |
Names: | IRF5 |
Organisms: | Homo sapiens |
Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | Site type: dimeric; SELEX cycle: 3, HT-SELEX |
Length: | 14 |
Consensus: | cCGAAACCGAAmCy |
Weblogo: | |
PSSM: | P0 A C G T 01 35 169 22 42 c 02 10 177 17 38 C 03 15 3 357 21 G 04 223 2 6 7 A 05 224 5 4 44 A 06 225 0 5 1 A 07 1 180 0 4 C 08 0 182 0 37 C 09 105 30 365 8 G 10 224 11 7 1 A 11 206 6 25 40 A 12 223 84 12 15 m 13 29 171 25 22 C 14 22 80 23 157 y |
Type: | Heterodimer |
Binding TFs: | Q13568 (Interferon regulatory factor transcription factor, Interferon-regulatory factor 3) IRF5_full (Interferon regulatory factor transcription factor, Interferon-regulatory factor 3) Q13568 |
Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Ourthiague DR, Birnbaum H, Ortenlöf N, Vargas JD, Wollman R, Hoffmann A. Limited specificity of IRF3 and ISGF3 in the transcriptional innate-immune response to double-stranded RNA. J Leukoc Biol 98:119-28 (2015). [Pubmed] |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.