DNA Binding Motif

Accessions: 2irf_GH (3D-footprint 20231221)
Names: INTERFERON REGULATORY FACTOR 2
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX.
Length: 9
Consensus: AnGTgnAag
Weblogo:
PSSM: P0 A C G T
01 96 0 0 0 A
02 24 24 24 24 n
03 0 0 96 0 G
04 0 0 0 96 T
05 13 13 54 16 g
06 24 24 24 24 n
07 96 0 0 0 A
08 50 13 20 13 a
09 13 16 54 13 g
Binding TFs: 2irf_G / 2irf_H (Interferon regulatory factor transcription factor)
Binding Sites: 2irf_A
2irf_F
Publications: Fujii Y, Shimizu T, Kusumoto M, Kyogoku Y, Taniguchi T, Hakoshima T. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. The EMBO journal 18:5028-41 (1999). [Pubmed]

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