DNA Binding Motif

Accessions: 5hlh_FH (3D-footprint 20231221)
Names: MarR family transcriptional regulator
Organisms: Staphylococcus epidermidis, strain ATCC 35984 / RP62A
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the overoxidized AbfR bound to DNA
Length: 20
Consensus: CGATTnAGnnnnCTnAATCG
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 0 96 0 G
03 90 2 2 2 A
04 0 3 0 93 T
05 2 0 3 91 T
06 24 24 24 24 n
07 88 2 2 4 A
08 12 7 68 9 G
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 7 68 9 12 C
14 4 2 2 88 T
15 24 24 24 24 n
16 71 12 4 9 A
17 94 0 2 0 A
18 4 2 2 88 T
19 0 96 0 0 C
20 1 2 93 0 G
Binding TFs: 5hlh_F / 5hlh_H (MarR family, HxlR-like helix-turn-helix, Sugar-specific transcriptional regulator TrmB, Transcriptional regulator PadR-like family, FeoC like transcriptional regulator, MarR family, Winged helix DNA-binding domain)
Binding Sites: 5hlh_M / 5hlh_N
Publications: Liu G, Liu X, Xu H, Liu X, Zhou H, Huang Z, Gan J, Chen H, Lan L, Yang CG. Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J Am Chem Soc 139:1598-1608 (2017). [Pubmed]

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