DNA Binding Motif

						

			
Accessions: NR3C2_DBD (HumanTF 1.0), MA0727.1 (JASPAR 2024)

			
Names: NR3C2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 17
Consensus: krGwACAywrTGTwCyc
Weblogo: 
PSSM: P0      A      C      G      T
01   8406   6688  20193  12758      k
02  15033    226  26931    535      r
03     57      8  55731     60      G
04  17523   1377   6650  13654      w
05  30042     15     13      9      A
06      0  49953      5      0      C
07  33515     28   1053    221      A
08   7347  18273   3144  16489      y
09  17996   4833   8538  11062      w
10  22920   1933  14022   4023      r
11    401    996     22  43465      T
12      0      9  58888      0      G
13      4     23      3  44513      T
14  13789   7366   1346  18547      w
15     16  42687      9     83      C
16    560  25680    582  16504      y
17   9074  17397   7774   8792      c
Type: Heterodimer
Binding TFs: NR3C2_DBD (Zinc finger, C4 type (two domains))
P08235 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
P08235 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
P08235
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Sandelin A, Wasserman W.W. Prediction of nuclear hormone receptor response elements. Molecular endocrinology (Baltimore, Md.) 19:595-606 (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.