DNA Binding Motif

						

			
Accessions: 1egw_AB (3D-footprint 20231221)

			
Names: MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF MEF2A CORE BOUND TO DNA
Length: 10
Consensus: CTannnnTAg
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0      0     96      T
03     54     13     13     16      a
04     24     24     24     24      n
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08      0      0      0     96      T
09     96      0      0      0      A
10     13     13     54     16      g
Type: Heterodimer
Binding TFs: 1egw_A (SRF-type transcription factor (DNA-binding and dimerisation domain))
1egw_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 1egw_E
1egw_F
			
Publications: Santelli E, Richmond T.J. Crystal structure of MEF2A core bound to DNA at 1.5 A resolution. Journal of molecular biology 297:437-49 (2000). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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